Therapeutic potential of inhibitors

The therapeutic potential of cyclophilin inhibitors spans a wide range of applications: Acute diseases (traumatic injuries, necroinflammatory diseases such as acute pancreatitis, myocardial infarction and stroke, sterile sepsis), chronic inflammatory diseases (joints, airways, eyes, gut), chronic degenerative and mitochondrial diseases (muscles, eyes and hearing), neurodegenerative and neuroinflammatory diseases (MS, ALS, Parkinson’s and Alzheimer’s disease, epilepsy), virus infections, fibrosis of various organs, and tumours.

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