Tools and assets
Cypralis has assembled a collection of approximately 2,000 drug-like compounds encompassing three different chemical families: cyclosporins, peptolides and cyprolides. These compounds span a wide range of different profiles of isoform specificity of inhibition, distribution properties, and include compounds suitable for oral, parenteral, or topical administration. The compounds can be used as tools for pharmacological disease validation, as starting points for medicinal chemistry optimisation programmes but also as scientific tools to investigate the role of cyclophilins in a given biological context.
A number of patent applications and granted patents secure the IP rights on compounds, their uses and manufacturing processes.
Please contact us to explore opportunities for collaboration or investment.